Layered Functional Network Analysis of Gene Expression in Human Heart Failure 英文参考文献.docVIP

LayeredFunctionalNetworkAnalysisofGeneExpression inHumanHeartFailure WenliangZhu,LeiYang,ZhiminDu* InstituteofClinicalPharmacology,TheSecondAffiliatedHospitalofHarbinMedicalUniversity,TheUniversityKeylaboratoryofHeiLongJiangProvince,Heilongjiang, China Abstract Background:Althoughdilatedcardiomyopathy(DCM)isaleadingcauseofheartfailure(HF),themechanismunderlying DCM is not well understood. Previously, it has been demonstrated that an integrative analysis of gene expression and protein-proteininteraction(PPI)networkscanprovideinsightsintothemolecularmechanismsofvariousdiseases.Inthis studywede