红花注射液致过敏性休克17例文献分析.PDFVIP

红花注射液致过敏性休克17例文献分析 ＊ # 计建军 ，王长江 （嘉兴学院附属第二医院，浙江嘉兴 314000） 中图分类号 R969.3 文献标志码 A 文章编号 1001-0408（2015）09-1192-03 DOI 10.6039/j.issn. 1001-0408.2015.09.15 摘 要 目的：探讨红花注射液致过敏性休克的一般规律和特点，为相关不良反应的防治提供参考。方法：检索中国期刊全文数 据库中收录的相关文献，对红花注射液致过敏性休克的病例进行统计分析。结果：统计的17例病例中，红花注射液所致过敏性休 克在女性患者中的发生比例为70.59％；在40岁以上中老年患者中的发生比例为70.59％；用药30min 内发生的比例高达76.47％； 58.82％的病例存在超说明书剂量用药；6例有联合用药情况；经抢救治疗后均恢复，无一例死亡。结论：红花注射液致过敏性休克 与诸多因素有关，临床医护人员应予以重视，在用药过程中应缓慢滴注、密切观察，如有异常应立即停药并采取积极措施救治。 关键词 红花注射液；过敏性休克；文献分析 Literature Analysis of 17Cases of Anaphylactic Shock Induced by Honghua Injection JI Jian-jun ，WANG Chang-jiang （The Second Affiliated Hospital of Jiaxing College ，Zhejiang Jiaxing 314000， China ） ABSTRACT OBJECTIVE ：To explore the general rules and characteristics of anaphylactic shock induced by Honghua injection and provide reference for the prevention and cure of related adverse reactions （ADR ）. METHODS ：Anaphylactic shock cases in- duced by Honghua injection were retrieved form the Chinese Journal Full-text Database and analyzed statistically. RESULTS ： Among the 17cases of ADR ，the occurrence proportion of anaphylactic shock induced by Honghua injection in female patients was 70.59％，70.59％was patients over 40 years old ，76.47％was occurred within 30 min ，58.82％was off-label drug and 6 cases were drug combination. They were recovered after emergency treatment with no fetal case. CONCLUSIONS ：Anaphylactic shock in- duced by Honghua injection is related to many factors. Clinical staff should pay attention to the medication progress by slow drip ， close observation and immediately stop and take positive measures for treatment if abnormal. KEY WORDS Honghua injection ；Anaphylactic shock ；Literature analysis 红花为菊科植物红花Carthamus tinctorius L. 的干燥花，性 在17例病例中，均有性别和年龄的记载，其中男性患者5 [1] 辛、温，归心、肝经，主要功能为活血通经、散瘀止痛 。红