Medication Adherence in Type 2 Diabetes The ENTRED Study 2007, a French Population-Based Study 英文参考文献.docVIP
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Medication Adherence in Type 2 Diabetes The ENTRED Study 2007, a French Population-Based Study 英文参考文献
MedicationAdherenceinType2Diabetes:TheENTRED
Study2007,aFrenchPopulation-BasedStudy
MichelTiv1,Jean-Franc?oisViel1,Fre′de′ricMauny1,EvelineEschwe`ge2,AlainWeill3,Ce′cileFournier4,
AnneFagot-Campagna5,AlfredPenfornis6*
1MedicalInformationDepartment,UniversityHospitalofBesanc?on,Besanc?on,France,2InstitutNationaldelaSante′etdelaRechercheMe′dicale(Inserm),Villejuif,France,
3French National Health Insurance Fund for Salaried Workers (CnamTS), Paris, France, 4Institute for Health Prevention and Education (Inpes), Saint Denis, France,
5Institute of Public Health Surveillance (InVS), Saint-Maurice, France, 6Department of Endocrinology-Metabolism and Diabetology-Nutrition, Jean Minjoz Hospital,
UniversityofFranche-Comte′,Besanc?on, France
Abstract
Background: Adherence to prescribed medications is a key dimension of healthcare quality. The aim of this large
population-based study was to evaluate self-reported medication adherence and to identify factors linked with poor
adherenceinpatientswithtype2diabetesinFrance.
Methodology: The ENTRED study 2007, a French national survey of people treated for diabetes, was based on a
representativesampleofpatientswhoclaimedreimbursementfororalhypoglycaemicagentsand/orinsulinatleastthree
timesbetweenAugust2006andJuly2007,andwhowererandomlyselectedfromthedatabaseofthetwomainNational
Health Insurance Systems. Medication adherence was determined using a six-item self-administered questionnaire. A
multinomialpolychotomouslogisticregressionmodelwasusedtoidentifyfactorsassociatedwithmedicationadherencein
the3,637personswithtype2diabetes.
PrincipalFindings:Thirtyninepercentofpatientsreportedgoodmedicationadherence,49%mediumadherenceand12%
pooradherence.Thefactorssignificantlyassociatedwithpooradherenceinmultivariateanalysisweresocio-demographic
factors:age,45years,non-Europeangeographicalorigin,financialdifficultiesandbeingprofessionallyactive;diseaseand
therapy-related factors: HbA1c.8% and existing diabetes complications; and health care-r
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