Perils of paradigm Complexity, policy design, and the Endocrine Disruptor Screening Program 英文参考文献.docVIP

Environmental Health: A Global Access Science Source BioMedCentral Commentary Open Access Perils of paradigm: Complexity, policy design, and the Endocrine Disruptor Screening Program Jason M Vogel* Address: Environmental Studies Program, University of Colorado, Campus Box 397, Boulder, CO 80309-0397, USA Email: Jason M Vogel* - vogelman157@ * Corresponding author Published: 08 February 2005 Received: 15 November 2004 Accepted: 08 February 2005 Environmental Health: A Global Access Science Source 2005, 4:2 doi:10.1186/1476-069X-4-2 This article is available from: /content/4/1/2 ? 2005 Vogel; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract The Endocrine Disruptor Screening Program (EDSP), mandated by the United States Congress in the Food Quality Protection Act of 1996, attempts to protect public health from adverse endocrine effects of synthetic chemical compounds by establishing a new testing regime. But the complexities and uncertainties of endocrine disruption and its broader regulatory and social context all but ensure the failure of this policy. This article addresses the issues facing EDSP comprehensively and in detail, in order to move beyond the current regulatory paradigm and foster discourse on a positive role for scientists in support of EDSPs end goal: to protect public health. Introduction The United States Environmental Protection Agency (EPA) created the Endocrine Disruptor Screening Program If such an effect is discovered, the [EPA] Administrator shall, as appropriate, take action under such statutory authority as is available...as is necessary to ensure the pro- tection of public health [2]. (EDSP) to regulate endocrine-disrupting chemicals