Peritoneal keratin granuloma associated with endometrioid adenocarcinoma of the uterine corpus 英文参考文献.docVIP

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Peritoneal keratin granuloma associated with endometrioid adenocarcinoma of the uterine corpus 英文参考文献.doc

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Peritoneal keratin granuloma associated with endometrioid adenocarcinoma of the uterine corpus 英文参考文献

Ueharaetal.DiagnosticPathology2011,6:104 /content/6/1/104 CASE REPORT OpenAccess Peritonealkeratingranulomaassociatedwith endometrioidadenocarcinomaoftheuterine corpus KeiichiroUehara1,MasanoriYasuda1,TakayaIchimura1,HiroshiYamaguchi1,KojiNagata1,HidekazuKayano2, AtsushiSasaki2,Shin-ichiMurata1andMichioShimizu1* Abstract Wepresenta69-year-oldwomanwithachiefcomplaintofpostmenopausalbleeding.Shewasdiagnosedas havinganendometrioidadenocarcinomabybiopsy,andunderwentatotalabdominalhysterectomy.Atthetime ofsurgery,granulationtissue-likenoduleswerefoundontheperitonealserosaoftheuterus.Intheintraoperative cytologyofperitonealwashing,atypicalcellswerenoted.Theintraoperativefrozensectionoftheperitoneal nodulerevealedgranulationtissuewithproliferatingmesothelialcells.Microscopicexaminationofthepermanent sectionshowedkeratingranulomaswithoutviableadenocarcinomacellsontheserosalsurfaceoftheovaries, fallopiantubesandbroadligaments.Postoperativechemotherapywasadministered.Shehasbeenalivewithno evidenceofrecurrencefor6monthspostoperatively.Itshouldbenotedthattheprognosisofcasesinperitoneal keratingranulomawithoutviablecancercellsisfavorable,andthatthehistologicalexaminationisessentialforits diagnosis. VirtualSlides:Thevirtualslide(s)forthisarticlecanbefoundhere:http://www.diagnosticpathology.diagnomx.eu/ vs/7119869525769574. Keywords:endometrioidadenocarcinoma,peritonealkeratingranuloma,squamousdifferentiation,uterinecorpus Background Peritoneal keratin granuloma has been described in adenocarcinoma of the uterine corpus and review the literature. cases of endometrioid adenocarcinoma with squamous differentiationoftheuterus,ovaryandatypicalpolypoid Casepresentation adenomyoma, although the number is limited [1-9]. A69-year-oldJapanesewomanwithnopreviousmedical These cases may resemble tumor implants grossly and historypresentedwithpostmenopausalbleeding.Herfirst microscopically,andmostcaseshavebeendescribedas periodstartedattheageof16,andstoppedattheageof keratin gran