Prevalence and Associated Factors of Diabetes and Impaired Fasting Glucose in Chinese Hypertensive Adults Aged 45 to 75 Years 英文参考文献.docVIP

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Prevalence and Associated Factors of Diabetes and Impaired Fasting Glucose in Chinese Hypertensive Adults Aged 45 to 75 Years 英文参考文献.doc

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Prevalence and Associated Factors of Diabetes and Impaired Fasting Glucose in Chinese Hypertensive Adults Aged 45 to 75 Years 英文参考文献

PrevalenceandAssociatedFactorsofDiabetesand ImpairedFastingGlucoseinChineseHypertensiveAdults Aged45to75Years XianhuiQin1.,JianpingLi2.,YanZhang2,WeiMa2,FangfangFan2,BinyanWang1,HouxunXing3, GenfuTang4,XiaobinWang5,XinXu6,XipingXu6*,YongHuo2* 1InstituteforBiomedicine,AnhuiMedicalUniversity,Hefei,China,2DepartmentofCardiology,PekingUniversityFirstHospital,Beijing,China,3LianyungangCenterfor Advanced Research in Cardiovascular Diseases, Lianyungang, China, 4School of Health Administration, Anhui Medical University, Hefei, China, 5Department of Population,FamilyandReproductiveHealth,CenterontheEarlyLifeOriginsofDisease,JohnsHopkinsUniversityBloombergSchoolofPublicHealth,Baltimore,Maryland, UnitedStatesofAmerica,6InstituteofNephrology,SouthernMedicalUniversity,Guangzhou,China Abstract Objective:Thisstudyexaminedtheprevalenceofimpairedfastingglucose(IFG)anddiabetesandtheirassociatedfactorsin 17,184Chinesehypertensiveadultsaged45–75years. Methods: A cross-sectional investigation was carried out in a rural area of Lianyungang, China. Previously undiagnosed diabetes [fasting plasma glucose (FPG) $7.0mmol/l] and IFG (6.1–6.9mmol/l) were defined based on FPG concentration. Previously diagnosed diabetes was determined on the basis of self-report. Total diabetes included both previously diagnoseddiabetesandpreviouslyundiagnoseddiabetes. Results: The prevalence of previously diagnosed diabetes, undiagnosed diabetes, and IFG were 3.4%, 9.8%, and 14.1%, respectively.About74.2%oftheparticipantswithdiabeteshadnotpreviouslybeendiagnosed.Inthemultivariablelogistic- regression model, older age, men, antihypertensive treatment, obesity (BMI $25kg/m2), abdominal obesity (waist circumference$90cmformenand$80cmforwomen),non-currentsmoking,afamilyhistoryofdiabetes,higherheartrate, lowerphysicalactivitylevels,andinlandresidence(versuscoastal)weresignificantlyassociatedwithbothtotaldiabetesand previouslyundiagnosed diabetes.Furthermore, methylene-tetrahydrofolate reductase (MTHFR)677TTgenot