Reconstruction of regulatory and metabolic pathways in metal-reducing δ-proteobacteria 英文参考文献.docVIP

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Reconstruction of regulatory and metabolic pathways in metal-reducing δ-proteobacteria 英文参考文献.doc

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Reconstruction of regulatory and metabolic pathways in metal-reducing δ-proteobacteria 英文参考文献

Open Access rch 2004RodionovetVReal.lumesea5, Issue 11, Article R90 Reconstruction of regulatory and metabolic pathways in metal-reducing δ-proteobacteria Dmitry A Rodionov*, Inna Dubchak?, Adam Arkin?§?, Eric Alm? and Mikhail S Gelfand*￥ Addresses: *Institute for Information Transmission Problems, Russian Academy of Sciences, Bolshoi Karetny per. 19, Moscow 127994, Russia. ?Genomics Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. ?Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. §Howard Hughes Medical Institute, Berkeley, CA 94720, USA. ?University of California, Berkeley, CA 94720, USA. ￥State Scientific Center GosniiGenetika, 1st Dorozhny pr. 1, Moscow 117545, Russia. Correspondence: Dmitry A Rodionov. E-mail: rodionov@genetika.ru Published: 22 October 2004 Genome Biology 2004, 5:R90 Received: 2 July 2004 Revised: 20 September 2004 Accepted: 30 September 2004 The electronic version of this article is the complete one and can be found online at /2004/5/11/R90 ? 2004 Rodionov et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. ReconstructionpapthAwayusdsyugogf ethsoftesregulatorygtehnaettpichyalnodgandernegemetabolicutilcaatlolyrydfavcepathwaystrosresdienltsae-vinperrometal-reducingatleboiboascytnetrhiaeshisa,vdelta-proteobacteriametale homionologhomeostasis,ous regulatorstressy compresponse,onents./andp energy metabolism Abstract Background: Relatively little is known about the genetic basis for the unique physiology of metal- reducing genera in the delta subgroup of the proteobacteria. The recent availability of complete finished or draft-quality genome sequences for seven representatives allowed us to investigate the genetic and regulator