儿童神经母细胞瘤伴骨转移的MSCT诊断.pdfVIP

1766 • 实用放射学杂志 2016 年 11 月第 32 卷第 11 期 J Pract Radiol , Nov. 2016 , Vo l. 32 , No.11 儿童神经母细胞瘤伴骨转移的 MSCT 诊断 周俊霖1 ，苗 静气黄素华l ，丁 山1 ，朱才姊1 ，徐红艳3 ，罗位鑫1 (江西省儿童医院 I 放射科;2 儿内科;3 病理科，江西 南昌 330006) 摘要:目的 探讨儿童神经母细胞瘤(NB)伴全身骨转移的临床特征及MSCT诊断. 方法 回顾性分析 10 例 NB伴骨转移患 儿的临床及 MSCT 资料，分析其影像学特征。 10 例均行腹部 CT 平扫及增强检查，其中胸部和头颅 CT 平扫及增强检查分别为 3 例和 4 例.结果 10 例 NB 患儿均伴有骨转移，其中 3 例伴有肝转移，另 3 例伴有远处淋巴结转移. 4 例为颅面骨转移，4 例为骨 盆转移，2 例为脊柱转移，均表现为溶骨性骨质破坏，其周软组织肿块可见钙化及垂直状骨针。增强后软组织肿块及邻近脑膜有不 均匀轻度强化。结论 NB 骨转移的临床及 MSCT 均有一定特征性，MSCT 对本病的诊断有重要价值. 关键词:神经母细胞瘤;骨锵;转移;计算机体层成像 ∞1: 10. 3969/ i. issn. 1002- 1671. 2016.1 1. 030 中图分类号:R814.42 ;R730.264 文献标志码:A 文章编号:1002一1671(2016)11 -1766一04 MSCT findings of children metastatic neuroblastoma in bone ZHOU lunlin , MIAO ling , HUANG Suhua , DING Shan , ZHUCaidi , XU Hongyan , LUO 1 iaxin (Department of Radiology ,]i angxi Provinçial Children s Hospital ,Nançhang 330006 ,China) Abstract :Objective To explore the MSCT features of children metastatic neuroblastoma (NB) in bone. Methods The imaging findings in 10 patients with children metastatic NB in bone were analyzed retrospectively. Ten patients underwent plain and contrast- enhanced CT scan of abdomen. Additionally , 3 patients underwent plain and contrast砸enhanced CT scan of chest , 4 patients under- went plain and contrast-enhanced CT scan of head . Results Among the 10 patients , bone metastasis involved skull (4 patient外 ， pel- vis(4 patients) , spine(2 patients) ,besides liver metastasis (3 patients) and distant Iymph node metastasis (3 patients). The 10 cases were all characterized by the bone destruction of osteolysis , calcification and 5piculated periosteal reaction in soft tissue masses near- by . Slight heterogeneous enhancement5 in the 50ft tissue mass and adjacent meninge were obser