Sickle cell nephropathy with diffuse proliferative lupus nephritis a case report 英文参考文献.docVIP

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Sickle cell nephropathy with diffuse proliferative lupus nephritis a case report 英文参考文献.doc

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Diagnostic Pathology BioMedCentral Case Report Open Access Sickle cell nephropathy with diffuse proliferative lupus nephritis: a case report Kamal V Kanodia*1, Aruna V Vanikar1, Kamal R Goplani2, Sonia B Gupta2 and Hargovind L Trivedi2 Address: 1Department of Pathology, Laboratory Medicine and Transfusion Services, and Immunohematology, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases and Research Centre and Dr. H. L. Trivedi Institute of Transplantation Sciences, Civil Hospital Campus, Asarwa, Ahmedabad, India and 2Department of Nephrology and Transplantation Medicine, G.R. Doshi and K.M. Mehta Institute of Kidney Diseases and Research Centre and Dr. H. L. Trivedi Institute of Transplantation Sciences, Civil Hospital Campus, Asarwa, Ahmedabad, India Email: Kamal V Kanodia* - kamalkanodia@; Aruna V Vanikar - vanikararuna@; Kamal R Goplani - kamalgoplani@; Sonia B Gupta - drsonia@; Hargovind L Trivedi - ikdrcad1@sancharnet.in * Corresponding author Published: 28 February 2008 Received: 14 August 2007 Accepted: 28 February 2008 Diagnostic Pathology 2008, 3:9 doi:10.1186/1746-1596-3-9 This article is available from: /content/3/1/9 ? 2008 Kanodia et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Background: Sickle cell nephropathy (SCN) is an important cause of mortality in patients with sickle cell disease. SCA with systemic lupus erythematosus (SLE) is known in children and less common in adults, however diffuse proliferative lupus nephritis (DPLN) with SCN has rarely been reported in adults. It requires early diagnosis and aggressive management. Case presentation: We present here a 35 years old lady with sickle cell disease who presented with edema, dyspnoea on exertion, pyuria and had raise