Single trial somatosensory evoked potential extraction with ARX filtering for a combined spinal cord intraoperative neuromonitoring technique 英文参考文献.docVIP

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Single trial somatosensory evoked potential extraction with ARX filtering for a combined spinal cord intraoperative neuromonitoring technique 英文参考文献.doc

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Single trial somatosensory evoked potential extraction with ARX filtering for a combined spinal cord intraoperative neuromonitoring technique 英文参考文献

BioMedical Engineering OnLine BioMedCentral Research Open Access Single trial somatosensory evoked potential extraction with ARX filtering for a combined spinal cord intraoperative neuromonitoring technique Lorenzo Rossi*1,2, Anna Maria Bianchi2, Anna Merzagora2,3, Alberto Gaggiani1, Sergio Cerutti2 and Francesco Bracchi1 Address: 1Department of Human Physiology, University of Milan, Italy, 2Department of Biomedical Engineering, Polytechnic of Milan, Italy and 3School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA, USA Email: Lorenzo Rossi* - lorenzo.rossi@polimi.it; Anna Maria Bianchi - annamaria.bianchi@polimi.it; Anna Merzagora - am396@; Alberto Gaggiani - lab6@unimi.it; Sergio Cerutti - cerutti@biomed.polimi.it; Francesco Bracchi - francesco.bracchi@unimi.it * Corresponding author Published: 04 January 2007 Received: 29 June 2006 Accepted: 04 January 2007 BioMedical Engineering OnLine 2007, 6:2 doi:10.1186/1475-925X-6-2 This article is available from: /content/6/1/2 ? 2007 Rossi et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: When spinal cord functional integrity is at risk during surgery, intraoperative neuromonitoring is recommended. Tibial Single Trial Somatosensory Evoked Potentials (SEPs) and H-reflex are here used in a combined neuromonitoring method: both signals monitor the spinal cord status, though involving different nervous pathways. However, SEPs express a trial-to-trial variability that is difficult to track because of the intrinsic low signal-to-noise ratio. For this reason single trial techniques are needed to extract SEPs from the background EEG. Methods: The analysis is performed off line on data record