Susceptibility to heat wave-related mortality a follow-up study of a cohort of elderly in Rome 英文参考文献.docVIP

Environmental Health BioMedCentral Research Open Access Susceptibility to heat wave-related mortality: a follow-up study of a cohort of elderly in Rome Patrizia Schifano*, Giovanna Cappai, Manuela De Sario, Paola Michelozzi, Claudia Marino, Anna Maria Bargagli and Carlo A Perucci Address: Department of Epidemiology, Local Health Authority Rome E, Rome, Italy Email: Patrizia Schifano* - schifano@asplazio.it; Giovanna Cappai - cappai@asplazio.it; Manuela De Sario - desario@asplazio.it; Paola Michelozzi - michelozzi@asplazio.it; Claudia Marino - marino@asplazio.it; Anna Maria Bargagli - bargagli@asplazio.it; Carlo A Perucci - perucci@asplazio.it * Corresponding author Published: 12 November 2009 Received: 10 March 2009 Accepted: 12 November 2009 Environmental Health 2009, 8:50 doi:10.1186/1476-069X-8-50 This article is available from: /content/8/1/50 ? 2009 Schifano et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Few studies have identified specific factors that increase mortality during heat waves. This study investigated socio-demographic characteristics and pre-existing medical conditions as effect modifiers of the risk of dying during heat waves in a cohort of elderly residents in Rome. Methods: A cohort of 651,195 residents aged 65 yrs or older was followed from 2005 to 2007. During summer, heat wave days were defined according to month-specific thresholds of maximum apparent temperature. The adjusted relative risk of dying during heat waves was estimated using a Poisson regression model including all the considered covariates. Risk differences were also calculated. All analyses were run separately for the 65-74 and 75+ age groups. Results: In the 65