Synergistic effect of simvastatin and ezetimibe on lipid and pro-inflammatory profiles in pre-diabetic subjects 英文参考文献.docVIP

Kater et al. Diabetology Metabolic Syndrome 2010, 2:34 /content/2/1/34 RESEARCH Open Access Synergistic effect of simvastatin and ezetimibe on Research lipid and pro-inflammatory profiles in pre-diabetic subjects Ana-Lucia A Kater1, Marcelo C Batista2 and Sandra RG Ferreira*3 Abstract Background: Ezetimibe specifically blocks the absorption of dietary and biliary cholesterol and plant sterols. Synergism of ezetimibe-statin therapy on LDL-cholesterol has been demonstrated, but data concerning the pleiotropic effects of this combination are controversial. Objective: This open-label trial e