Synthesis and Antimicrobial Activity of Some New Benzimidazole Derivatives 英文参考文献.docVIP

Molecules 2000, 5, 1429–1438 molecules ISSN 1420-3049 Synthesis and Antimicrobial Activity of Some New Benzimidazole Derivatives Afaf H. El-masry, H. H. Fahmy and S. H. Ali Abdelwahed Therapeutical Chemistry Department. National Research Centre, Dokki, Cairo, Egypt. Fax: 00202 3370931. E-mail: elmasry_afaf@. Received: 10 January 2000; in revised form 5 August 2000 / Accepted: / Published: 22 December 2000 Abstract: Reaction of 3-(2-methylbenzimidazol-1-yl)propanoic acid hydrazide (1) with CS2/KOH gave oxadiazole 2 which underwent Mannich reaction to give 3. Compound 2 was treated w