T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles 英文参考文献.docVIP

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T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles 英文参考文献.doc

T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles 英文参考文献

Lawetal.ArthritisResearchTherapy2012,14:R118 /content/14/3/R118 RESEARCH ARTICLE OpenAccess T-cellautoreactivitytocitrullinatedautoantigenic peptidesinrheumatoidarthritispatientscarrying HLA-DRB1sharedepitopealleles SoiChengLaw1?,ShaynaStreet1?,Chien-HsiungAlanYu1,ChristelleCapini1,SakoontallaRamnoruth1, HendrikJNel1,ElinevanGorp1,ClaireHyde1,KimLau2,HelenPahau1,AnthonyWPurcell2andRanjenyThomas1* Abstract Introduction:Anti-citrullinatedpeptideantibodiesarefoundinrheumatoidarthritis(RA)patientswithHLA-DRb chainsencodingthesharedepitope(SE)sequence.Citrullinationincreasesself-antigenimmunogenic

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