Temporal course of cerebrospinal fluid dynamics and amyloid accumulation in the aging rat brain from three to thirty months 英文参考文献.docVIP
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Temporal course of cerebrospinal fluid dynamics and amyloid accumulation in the aging rat brain from three to thirty months 英文参考文献
Chiuetal.FluidsandBarriersoftheCNS2012,9:3
/content/9/1/3
FLUIDS AND BARRIERS
OF THE CNS
RESEARCH
OpenAccess
Temporalcourseofcerebrospinalfluiddynamics
andamyloidaccumulationintheagingratbrain
fromthreetothirtymonths
CatherineChiu1,MilesCMiller1,IliasNCaralopoulos1,MichaelSWorden2,ThomasBrinker1,ZacharyNGordon1,
ConradEJohanson1andGeraldDSilverberg1*
Abstract
Background:AmyloidaccumulationinthebrainparenchymaisahallmarkofAlzheimer’sdisease(AD)andisseen
innormalaging.Alterationsincerebrospinalfluid(CSF)dynamicsarealsoassociatedwithnormalagingandAD.
ThisstudyanalyzedCSFvolume,productionandtur
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