The 5-HTTLPR polymorphism of the serotonin transporter gene and short term behavioral response to methylphenidate in children with ADHD 英文参考文献.docVIP

Thakur et al. BMC Psychiatry 2010, 10:50 /1471-244X/10/50 RESEARCH ARTICLE Open Access The 5-HTTLPR polymorphism of the serotonin Research article transporter gene and short term behavioral response to methylphenidate in children with ADHD Geeta A Thakur1,4, Natalie Grizenko2,4, Sarojini M Sengupta4, Norbert Schmitz2,4 and Ridha Joober*1,2,3,4 Abstract Background: Animal models of ADHD suggest that the paradoxical calming effect of methylphenidate on motor activity could be mediated through its action on serotonin transmission. In this study, we have investigated the relationship bet