The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue 英文参考文献.docVIP
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The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue 英文参考文献
Robertsetal.GenomeBiology2011,12:R75
/2011/12/8/R75
RESEARCH
OpenAccess
ThecontrastingrolesofPPARδandPPARgin
regulatingthemetabolicswitchbetween
oxidationandstorageoffatsinwhiteadipose
tissue
LeeDRoberts1,2,AndrewJMurray3,DavidMenassa3,TomAshmore1,AndrewWNicholls4and
JulianLGriffin1,2,5,6*
Abstract
Background:Thenuclearreceptorsperoxisomeproliferator-activatedreceptorg(PPARg)andperoxisome
proliferator-activatedreceptorδ(PPARδ)playcentralrolesinregulatingmetabolisminadiposetissue,aswellas
beingtargetsforthetreatmentofinsulinresistance.WhiletheroleofPPARginregulatinginsulinsensitivityhas
beenw
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