The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue 英文参考文献.docVIP

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The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue 英文参考文献.doc

The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue 英文参考文献

Robertsetal.GenomeBiology2011,12:R75 /2011/12/8/R75 RESEARCH OpenAccess ThecontrastingrolesofPPARδandPPARgin regulatingthemetabolicswitchbetween oxidationandstorageoffatsinwhiteadipose tissue LeeDRoberts1,2,AndrewJMurray3,DavidMenassa3,TomAshmore1,AndrewWNicholls4and JulianLGriffin1,2,5,6* Abstract Background:Thenuclearreceptorsperoxisomeproliferator-activatedreceptorg(PPARg)andperoxisome proliferator-activatedreceptorδ(PPARδ)playcentralrolesinregulatingmetabolisminadiposetissue,aswellas beingtargetsforthetreatmentofinsulinresistance.WhiletheroleofPPARginregulatinginsulinsensitivityhas beenw

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