The effect on survival of continuing chemotherapy to near death 英文参考文献.docVIP

Saitoetal.BMCPalliativeCare2011,10:14 /1472-684X/10/14 RESEARCH ARTICLE OpenAccess Theeffectonsurvivalofcontinuing chemotherapytoneardeath AkikoMSaito1,MaryBethLandrum2,BridgetANeville3,JohnZAyanian2,4 andCraigCEarle5* Abstract Background:Overuseofanti-cancertherapyisanimportantquality-of-careissue.Anaggressiveapproachto treatmentcanhavenegativeeffectsonqualityoflifeandcost,butitseffectonsurvivalisnotwell-defined. Methods:UsingtheSurveillance,Epidemiology,andEndResults-Medicaredatabase,weidentified7,879Medicare- enrolledpatientsaged65orolderwhodiedafterhavingsurvivedatleast3monthsafte