The Effects of Pregnenolone 16α-Carbonitrile Dosing on Digoxin Pharmacokinetics and Intestinal Absorption in the Rat 英文参考文献.docVIP

Pharmaceutics 2010, 2, 61-77; doi:10.3390/pharmaceutics2010061 OPEN ACCESS pharmaceutics ISSN 1999-4923 /journal/pharmaceutics Article The Effects of Pregnenolone 16α-Carbonitrile Dosing on Digoxin Pharmacokinetics and Intestinal Absorption in the Rat Simon Lowes 1,2, Iain S. Haslam 1,?, Britt-Marie Fihn 2, Constanze Hilgendorf 2,*, Johan E. Karlsson 2, Nicholas L. Simmons 1 and Anna-Lena Ungell 2 1 Epithelial Research Group, Institute for Cell and Molecular Biosciences, Medical School, Newcastle University, NE2 4HH, UK; E-Mails: simon.lowes@.uk (S.L.); Iain.haslam@ (I.S.H.); n.l.simmon