The gene expression profile of preclinical autoimmune arthritis and its modulation by a tolerogenic disease-protective antigenic challenge 英文参考文献.docVIP

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The gene expression profile of preclinical autoimmune arthritis and its modulation by a tolerogenic disease-protective antigenic challenge 英文参考文献.doc

Yuetal.ArthritisResearchTherapy2011,13:R143 /content/13/5/R143 RESEARCH ARTICLE OpenAccess Thegeneexpressionprofileofpreclinical autoimmunearthritisanditsmodulationbya tolerogenicdisease-protectiveantigenicchallenge HuaYu1,ChangwanLu2,3,MingTTan3andKamalDMoudgil1,4* Abstract Introduction:Autoimmuneinflammationisacharacteristicfeatureofrheumatoidarthritis(RA)andotherautoimmune diseases.Inthenaturalcourseofhumanautoimmunediseases,itisratherdifficulttopinpointtheprecisetimingofthe initialeventthattriggersthecascadeofpathogeniceventsthatlaterculminateintoclinicallyovertdisease.Therefore,it isac

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