The genetic regulation of the terminating phase of liver regeneration 英文参考文献.docVIP

Nyg?rdetal.ComparativeHepatology2012,11:3 /content/11/1/3 RESEARCH OpenAccess Thegeneticregulationoftheterminatingphase ofliverregeneration IngvildENyg?rd1*,KimEMortensen1,JakobHedegaard2,LeneNConley2,TrineKalstad3,ChristianBendixen2 andArthurRevhaug3 Abstract Background:Afterpartialhepatectomy(PHx),theliverregenerationprocessterminateswhenthenormalliver- mass/body-weightratioof2.5%hasbeenre-established.Toinvestigatethegeneticregulationoftheterminating phaseofliverregeneration,weperformeda60%PHxinaporcinemodel.Liverbiopsiesweretakenatthetimeof resection,afterthreeweeksanduponterminationthesixt