原创力文档The genomic landscape shaped by selection on transposable elements across 18 mouse strains 英文参考文献.docVIP
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The genomic landscape shaped by selection on transposable elements across 18 mouse strains 英文参考文献
Nell?keretal.GenomeBiology2012,13:R45
/2012/13/6/R45
RESEARCH
OpenAccess
Thegenomiclandscapeshapedbyselectionon
transposableelementsacross18mousestrains
ChristofferNell?ker1*?,ThomasMKeane2?,BinnazYalcin3,KimWong2,AvigailAgam1,3,TGrantBelgard1,4,5,
JonathanFlint3,DavidJAdams2,WayneNFrankel6andChrisPPonting1,2*
Abstract
Background:Transposableelement(TE)-derivedsequencedominatesthelandscapeofmammaliangenomesand
canmodulategenefunctionbydysregulatingtranscriptionandtranslation.OurcurrentknowledgeofTEsin
laboratorymousestrainsislimitedprimarilytothosepresentintheC57BL/6Jreferencegenome,withmost
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