The impact of IL-1 modulation on the development of lipopolysaccharide-induced cognitive dysfunction 英文参考文献.docVIP

Terrando et al. Critical Care 2010, 14:R88 /content/14/3/R88 RESEARCH Open Access The impact of IL-1 modulation on the development Research of lipopolysaccharide-induced cognitive dysfunction Niccolò Terrando*1,2, António Rei Fidalgo1, Marcela Vizcaychipi1, Mario Cibelli1,4, Daqing Ma1, Claudia Monaco3, Marc Feldmann3 and Mervyn Maze*1,2 Abstract Introduction: The impact of pro-inflammatory cytokines on neuroinflammation and cognitive function after lipopolysaccharide (LPS) challenge remains elusive. Herein we provide evidence that there is a temporal correlation between high-mobility gr