The uvrA, uvrB and uvrC genes are required for repair of ultraviolet light induced DNA photoproducts in Halobacterium sp. NRC-1 英文参考文献.docVIP

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The uvrA, uvrB and uvrC genes are required for repair of ultraviolet light induced DNA photoproducts in Halobacterium sp. NRC-1 英文参考文献.doc

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The uvrA, uvrB and uvrC genes are required for repair of ultraviolet light induced DNA photoproducts in Halobacterium sp. NRC-1 英文参考文献

Saline Systems BioMedCentral Research Open Access The uvrA, uvrB and uvrC genes are required for repair of ultraviolet light induced DNA photoproducts in Halobacterium sp. NRC-1 David J Crowley*?1, Ivan Boubriak?2, Brian R Berquist4, Monika Clark3, Emily Richard1, Lynn Sullivan1, Shiladitya DasSarma4,5 and Shirley McCready2 Address: 1Natural Sciences Department, Assumption College, 500 Salisbury Street, Worcester, Massachusetts 01609 USA, 2School of Life Sciences, Oxford Brookes University, Oxford, OX3 0BP, UK, 3Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee 37235 USA, 4University of Maryland Biotechnology Institute Center of Marine Biotechnology Baltimore, Maryland 21042 USA and 5Greenebaum Cancer Center, University of Maryland, Baltimore, Maryland 21201 USA Email: David J Crowley* - dacrowle@; Ivan Boubriak - iboubriak@brookes.ac.uk; Brian R Berquist - berquist@; Monika Clark - monika.l.clark@; Emily Richard - erichard@; Lynn Sullivan - lsulliva@; Shiladitya DasSarma - dassarma@; Shirley McCready - sjmccready@brookes.ac.uk * Corresponding author ?Equal contributors Published: 13 September 2006 Received: 30 July 2006 Accepted: 13 September 2006 Saline Systems 2006, 2:11 doi:10.1186/1746-1448-2-11 This article is available from: /content/2/1/11 ? 2006 Crowley et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Sequenced archaeal genomes contain a variety of bacterial and eukaryotic DNA repair gene homologs, but relatively little is known about how these microorganisms actually perform DNA repair. At least some archaea, including the extreme halophile Halobacterium sp. NRC-1, are able to repair ultraviolet light (UV) induced DNA damage in the absence of light