- 1、本文档共2页,可阅读全部内容。
- 2、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
- 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
- 5、该文档为VIP文档,如果想要下载,成为VIP会员后,下载免费。
- 6、成为VIP后,下载本文档将扣除1次下载权益。下载后,不支持退款、换文档。如有疑问请联系我们。
- 7、成为VIP后,您将拥有八大权益,权益包括:VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 8、VIP文档为合作方或网友上传,每下载1次, 网站将根据用户上传文档的质量评分、类型等,对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
To dose or not to dose that is the (starch) question 英文参考文献
Kaplan Critical Care 2010,14:148
/content/14/3/148
COMMENTARY
To dose or not to dose: that is the (starch) question …
Lewis J Kaplan*
See related research by Boussekey et al., /content/14/2/R40
trials evaluating renal dysfunction are binary, in that ARF
Abstract
is present or absent; AKI is often not addressed. More-
The present study describes the impact on renal
function of a modern starch used for resuscitation
in the intensive care unit. The role of starch in renal
dysfunction, the importance of the de?nition of
acute kidney injury and acute renal failure, and
hyperoncoticity are reviewed.
over, the de? nitions used in non-RIFLE trials are often
based on a percentage change in creatinine (100%), a
creatinine threshold (2.0 mg%), and the need for dialysis
regardless of modality without specifying the triggering
criteria. Worse still, the HES and diluents used are vastly
di? erent between trials.
Boussekey and colleagues used a modern low
molecular weight and degree of substitution starch, and
Hydroxyethyl starch (HES) has been vili? ed, praised, or the diluent was not speci? ed but presumed to be 0.9%
largely ignored as a resuscitation ? uid depending on the
normal saline solution. Unfortunately, they did not report
on the presence of hyperchloremic metabolic acidosis
during their trial, a condition that is associated with
setting within which the HES is administere
e most
recent HES focus has been on renal injury when HES is
administered to patients with severe sepsis or septic reduced renal blood ? ow and reduced glomerular
shock. Boussekey and colleagues have provided us with a
single-center, 2-year view of how HES use in the intensive
care unit relates to renal function [1]. Several elements of
this study merit discussion.
? ltration rate. Patients in the study were divided into two
groups based on whether HES was or was not adminis-
tered at
您可能关注的文档
- Tight glycaemic control in the intensive care unit pitfalls in the testing of the concept 英文参考文献.doc
- Tight perioperative glucose control is associated with a reduction in renal impairment and renal failure in non-diabetic cardiac surgical patients 英文参考文献.doc
- Tied together like a woven hat Protective pathways to Alaska native sobriety 英文参考文献.doc
- Tiling microarray analysis of rice chromosome 10 to identify the transcriptome and relate its expression to chromosomal architecture 英文参考文献.doc
- Thyroid hormones and antibody response to sheep erythrocytes of dwarf and normal chickens selected for juvenile body weight 英文参考文献.doc
- TILLING to detect induced mutations in soybean 英文参考文献.doc
- Tilescope online analysis pipeline for high-density tiling microarray data 英文参考文献.doc
- Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model 英文参考文献.doc
- Time course of plasma gelsolin concentrations during severe sepsis in critically ill surgical patients 英文参考文献.doc
- Tightly Coupled Low Cost 3D RISSGPS Integration Using a Mixture Particle Filter for Vehicular Navigation 英文参考文献.doc
- 一年级道德与法治上册第二单元《校园生活真快乐》测试卷含完整答案【名师系列】.docx
- 一年级道德与法治上册第二单元《校园生活真快乐》测试卷附答案【能力提升】.docx
- 一年级道德与法治上册第二单元《校园生活真快乐》测试卷精品【实用】.docx
- 一年级道德与法治上册第二单元《校园生活真快乐》测试卷附完整答案(名师系列).docx
- 一年级道德与法治上册第二单元《校园生活真快乐》测试卷含答案(实用).docx
- 一年级上册道德与法治第二单元《校园生活真快乐》测试卷附答案(名师推荐).docx
- 一年级道德与法治上册第二单元《校园生活真快乐》测试卷【b卷】.docx
- 一年级道德与法治上册第二单元《校园生活真快乐》测试卷(满分必刷).docx
- 一年级道德与法治上册第二单元《校园生活真快乐》测试卷含完整答案(易错题).docx
- 一年级道德与法治上册第二单元《校园生活真快乐》测试卷及参考答案1套.docx
文档评论(0)