Update of Spectroscopic Data for 4-Hydroxydictyolactone and Dictyol E Isolated from a Halimeda stuposa — Dictyota sp. Assemblage 英文参考文献.docVIP

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Update of Spectroscopic Data for 4-Hydroxydictyolactone and Dictyol E Isolated from a Halimeda stuposa — Dictyota sp. Assemblage 英文参考文献.doc

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Update of Spectroscopic Data for 4-Hydroxydictyolactone and Dictyol E Isolated from a Halimeda stuposa — Dictyota sp. Assemblage 英文参考文献

Molecules 2012, 17, 2929-2938; doi:10.3390/moleculeOPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article Update of Spectroscopic Data for 4-Hydroxydictyolactone and Dictyol E Isolated from a Halimeda stuposa — Dictyota sp. Assemblage ? Simon P. B. Ovenden ?, Jonathan L. Nielson §, Catherine H. Liptrot ||, Richard H. Willis, Dianne M. Tapiolas, Anthony D. Wright ? and Cherie A. Motti * Australian Institute of Marine Science, PMB no. 3, Townsville MC, Townsville, 4810, Australia; E-Mails: r.willis@.au (R.H.W.); d.tapiolas@.au (D.M.T.) ? Present address: Defence Science Technology Organisation, 506 Lorimer St. Fishermans Bend, Victoria, 3207, Australia; E-Mail: simon.ovenden@.au § Present address: ACD Labs UK, Building A, Trinity Court, Wokingham Road, Bracknell, Berkshire, RG42 1PL, UK; E-Mail: jonathon.nielson@ || Present address: James Cook University, Townsville, Queensland 4811, Australia; E-Mail: catherine.liptrot@.au ? Present address: University of Hawaii, College of Pharmacy, 34 Rainbow Drive, Hilo, HI 96720, USA; E-Mail: adwright@ ? Dedication: We dedicate this paper to the late Peter Thomas Murphy (Townsville, Australia) for his passionate contributions to Australian natural products chemistry and marine biodiversity research. * Author to whom correspondence should be addressed; E-Mail: c.motti@.au; Tel.: +61-7-4753-4143; Fax: +61-7-4772-5852. Received: 7 February 2012; in revised form: 23 February 2012 / Accepted: 5 March 2012 / Published: 8 March 2012 Abstract: The methanol extract of an assemblage of Halimeda stuposa and a Dictyota sp., yielded three natural products characteristic of Dictyota sp., and one of Halimeda sp. These included the xenicane diterpene 4-hydroxydictyolactone (1), and the diterpenes dictyol E (2), 8?,11-dihydroxypachydictyol A (3) and indole-3-carboxaldehyde (4). A minor revision of 1 and new spectroscopic data for 1 and 2 are provided, along with associated anti-cancer activities of compounds