第十一章：细胞异常增生性疾病的分.pptVIP

* 4. 癌基因的功能与分类 根据原癌基因在细胞中的位置： 　1.与膜结合的蛋白，如src基因产物 　2.可溶性蛋白，如mos基因产物 　3.核蛋白，如myc基因产物 * 根据原癌基因表达产物的功能： 1.蛋白激酶类，如src家族（酪氨酸蛋白激酶类） 2.生长因子类 3.生长因子受体类 4.GTP结合蛋白类 5.核蛋白类（DNA结合蛋白），如myc家族 6.未知功能类 * The cellular oncogenes are inherent genes in cell and has its normal biological function, such as Stimulating normal cell growth, participating in the regulation of cell proliferation and differentiation, and meeting the requirements of cell renewal. The cell will continue to promote cell growth or the cells from death, and finally lead to carcinogenesis which not received the growth sign