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A Partial Least Squares based algorithm for parsimonious variable selection
Mehmoodetal.AlgorithmsforMolecularBiology2011,6:27
/content/6/1/27
RESEARCH
OpenAccess
APartialLeastSquaresbasedalgorithmfor
parsimoniousvariableselection
TahirMehmood1*,HaraldMartens2,SolveS?b?1,JonasWarringer2,3 andLarsSnipen1
Abstract
Background:Ingenomics,acommonlyencounteredproblemistoextractasubsetofvariablesoutofalargeset
ofexplanatoryvariablesassociatedwithoneorseveralquantitativeorqualitativeresponsevariables.Anexampleis
toidentifyassociationsbetweencodon-usageandphylogenybaseddefinitionsoftaxonomicgroupsatdifferent
taxonomiclevels.Maximumunderstandabilitywiththesmallestnumberof
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