原创力文档A phasing and imputation method for pedigreed populations that results in a single-stage genomic evaluation.docVIP
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A phasing and imputation method for pedigreed populations that results in a single-stage genomic evaluation
Hickeyetal.GeneticsSelectionEvolution2012,44:9
/content/44/1/9
G
enetics
Selection
Evolution
RESEARCH
OpenAccess
Aphasingandimputationmethodforpedigreed
populationsthatresultsinasingle-stagegenomic
evaluation
JohnMHickey1*,BrianPKinghorn1,BruceTier2,JuliusHJvanderWerf1,3andMatthewACleveland4
Abstract
Background:Efficient,robust,andaccurategenotypeimputationalgorithmsmakelarge-scaleapplicationof
genomicselectioncosteffective.Analgorithmthatimputesallelesoralleleprobabilitiesforallanimalsinthe
pedigreeandforallgenotypedsinglenucleotidepolymorphisms(SNP)providesaframeworktocombineall
pedigree,g
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