原创力文档A simple, practical and complete O-time Algorithm for RNA folding using the Four-Russians Speedup.docVIP
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A simple, practical and complete O-time Algorithm for RNA folding using the Four-Russians Speedup
FridandGusfieldAlgorithmsforMolecularBiology2010,5:13
/content/5/1/13
RESEARCH
OpenAccess
Asimple,practicalandcompleteO -time
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3 ?
n
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? logn ?
AlgorithmforRNAfoldingusingtheFour-
RussiansSpeedup
YelenaFrid*,DanGusfield
Abstract
Background:Theproblemofcomputationallypredictingthesecondarystructure(orfolding)ofRNAmolecules
wasfirstintroducedmorethanthirtyyearsagoandyetcontinuestobeanareaofactiveresearchand
development.ThebasicRNA-foldingproblemoffindingamaximumcardinality,non-crossing,matchingof
complimentarynucleotidesinanRNAsequenceoflengthn,hasanO(n3)-timedynamicprogrammingsolutio
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