Acute reversible inactivation of the bed nucleus of stria terminalis induces antidepressant-like effect in the rat forced swimming test.docVIP

Crestani et al. Behavioral and Brain Functions 2010, 6:30 /content/6/1/30 RESEARCH Open Access Acute reversible inactivation of the bed nucleus of Research stria terminalis induces antidepressant-like effect in the rat forced swimming test Carlos C Crestani1, Fernando HF Alves1, Fernando MA Correa1, Francisco S Guimar?es1 and Samia RL Joca*2 Abstract Background: The bed nucleus of stria terminalis (BNST) is a limbic forebrain structure involved in hypothalamo- pituitary-adrenal axis regulation and stress adaptation. Inappropriate adaptation to stress is thought to compromise the organisms