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Adenine oxidation by pyrite-generated hydroxyl radicals
Cohnetal.GeochemicalTransactions2010,11:2
/content/11/1/2
RESEARCH ARTICLE
OpenAccess
Adenineoxidationbypyrite-generatedhydroxyl
radicals
CoreyACohn1,3,ShawnCFisher2,BruceJBrownawell2,MartinAASchoonen1*
Abstract
Cellularexposuretoparticulatematterwithconcomitantformationofreactiveoxygenspecies(ROS)andoxidiza-
tionofbiomoleculesmayleadtonegativehealthoutcomes.Evaluatingtheparticle-inducedformationofROSand
theoxidationproductsfromreactionofROSwithbiomoleculesisusefulforgainingamechanisticunderstanding
ofparticle-inducedoxidativestress.Aqueoussuspensionsofpyriteparticleshavebeenshowntoformhydr
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