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Advanced paternal age is a risk factor for schizophrenia in Iranians
Naserbakhtetal.AnnalsofGeneralPsychiatry2011,10:15
/content/10/1/15
PRIMARY RESEARCH
OpenAccess
Advancedpaternalageisariskfactorfor
schizophreniainIranians
MortezaNaserbakht1,Hamid-RezaAhmadkhaniha2,3,4*,BaharehMokri5andCassandraLSmith6
Abstract
Background:Since1958many,butnotallstudieshavedemonstratedthatpaternalageisariskfactorfor
schizophrenia.Theremaybemanydifferentexplanationsfordifferencesbetweenstudies,includingstudydesign,
samplesize,collectioncriteria,heterogeneityandtheconfoundingeffectsofenvironmentalfactorsthatcanfor
exampleperturbepigeneticprogrammingandleadtoanincreaseindiseas
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