Antiviral Properties of ISG15.docVIP

Viruses 2010, 2, 2154-2168; doi:10.3390/v2102154 OPEN ACCESS viruses ISSN 1999-4915 /journal/viruses Review Antiviral Properties of ISG15 Deborah J. Lenschow 1,2 1 Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; E-Mail: dlenscho@; Tel.: +314-362-8637; Fax: +314-454-1091 Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA 2 Received: 2 August 2010; in revised form: 8 September 2010 / Accepted: 15 September 2010 / Published: 28 September 2010 Abstract: The type I interferon system plays a cri