Apoptosis signal-regulating kinase 1 is associated with the effect of claudin-6 in breast cancer.docVIP

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Apoptosis signal-regulating kinase 1 is associated with the effect of claudin-6 in breast cancer.doc

Apoptosis signal-regulating kinase 1 is associated with the effect of claudin-6 in breast cancer

Guoetal.DiagnosticPathology2012,7:111 /content/7/1/111 RESEARCH OpenAccess Apoptosissignal-regulatingkinase1isassociated withtheeffectofclaudin-6inbreastcancer YaxiongGuo1,XiaomingXu2,ZhijingLiu1,TingZhang1,XiaoweiZhang1,LipingWang1,MinWang1, YuanyuanLiu1,YanLu1,YunpengLiu3andChengshiQuan1* Abstract Background:Previousstudieshavedemonstratedthatclaudin-6functionsasacancersuppressorinhumanMCF-7 breastcancercells.Thegrowthinhibitoryeffectcouldbeattributedtoinhibitionofcellproliferationandinduction ofapoptosis.Thepurposeofthecurrentstudywastoexaminetheinvolvementofapoptosissignal-regulating kin

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