Apoptosis signal-regulating kinase 1 is associated with the effect of claudin-6 in breast cancer.docVIP
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Apoptosis signal-regulating kinase 1 is associated with the effect of claudin-6 in breast cancer
Guoetal.DiagnosticPathology2012,7:111
/content/7/1/111
RESEARCH
OpenAccess
Apoptosissignal-regulatingkinase1isassociated
withtheeffectofclaudin-6inbreastcancer
YaxiongGuo1,XiaomingXu2,ZhijingLiu1,TingZhang1,XiaoweiZhang1,LipingWang1,MinWang1,
YuanyuanLiu1,YanLu1,YunpengLiu3andChengshiQuan1*
Abstract
Background:Previousstudieshavedemonstratedthatclaudin-6functionsasacancersuppressorinhumanMCF-7
breastcancercells.Thegrowthinhibitoryeffectcouldbeattributedtoinhibitionofcellproliferationandinduction
ofapoptosis.Thepurposeofthecurrentstudywastoexaminetheinvolvementofapoptosissignal-regulating
kin
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