Approach to the A-B Ring System of Forskolin through Biotransformation of Toluene.docVIP

522 Molecules 2000, 5 Approach to the A-B Ring System of Forskolin through Biotransformation of Toluene V. Schapiro, G. Seoane and G. García Cátedra de Química Orgánica, Facultad de Química, Gral. Flores 2124, Universidad de la República, Montevideo, Uruguay E-mail: vschapir@bilbo.edu.uy Abstract: In the present work, we will intend to show that diol I, microbially derived from toluene using Pseudomonas putida 39D, is a suitable synthon for the synthesis of the A-B ring system of forskolin. The functionalization of diol I, to be used as ring-B, and the attempts of ri