Appropriate antibiotic dosing in severe sepsis and acute renal failure factors to consider.docVIP

González de Molina and Ferrer Critical Care 2011,15:175 /content/15/4/175 COMMENTARY Appropriate antibiotic dosing in severe sepsis and acute renal failure: factors to consider Francisco Javier González de Molina and Ricard Ferrer* 1 1,2 See related research by Seyler et al., /content/15/3/R137 patients use signi? cant resources and up to 60% die from their injuries [3]. Optimized antibiotic dosing may help reduce this burden; however, data to guide dosing in patients with severe sepsis/septic shock and multiple organ