Argatroban therapy for heparin-induced thrombocytopenia in ICU patients with multiple organ dysfunction syndrome a retrospective study.docVIP

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Argatroban therapy for heparin-induced thrombocytopenia in ICU patients with multiple organ dysfunction syndrome a retrospective study.doc

Argatroban therapy for heparin-induced thrombocytopenia in ICU patients with multiple organ dysfunction syndrome a retrospective study

Saugeletal.CriticalCare2010,14:R90 /content/14/3/R90 RESEARCH OpenAccess Argatrobantherapyforheparin-induced thrombocytopeniainICUpatientswithmultiple organdysfunctionsyndrome:aretrospective study BerndSaugel1*,VeitPhillip1,GeorgMoessmer2,RolandMSchmid1,WolfgangHuber1 Abstract Introduction:Heparin-inducedthrombocytopenia(HIT)isaserious,prothrombotic,immune-mediatedadverse reactiontriggeredbyheparintherapy.WhenHITisdiagnosedorsuspected,heparinsshouldbediscontinued,and analternative,fast-acting,parenteral,nonheparinanticoagulationsuchasargatrobanshouldbeinitiated.Limited andinconsistentdataexist

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