Argatroban therapy for heparin-induced thrombocytopenia in ICU patients with multiple organ dysfunction syndrome a retrospective study.docVIP
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Argatroban therapy for heparin-induced thrombocytopenia in ICU patients with multiple organ dysfunction syndrome a retrospective study
Saugeletal.CriticalCare2010,14:R90
/content/14/3/R90
RESEARCH
OpenAccess
Argatrobantherapyforheparin-induced
thrombocytopeniainICUpatientswithmultiple
organdysfunctionsyndrome:aretrospective
study
BerndSaugel1*,VeitPhillip1,GeorgMoessmer2,RolandMSchmid1,WolfgangHuber1
Abstract
Introduction:Heparin-inducedthrombocytopenia(HIT)isaserious,prothrombotic,immune-mediatedadverse
reactiontriggeredbyheparintherapy.WhenHITisdiagnosedorsuspected,heparinsshouldbediscontinued,and
analternative,fast-acting,parenteral,nonheparinanticoagulationsuchasargatrobanshouldbeinitiated.Limited
andinconsistentdataexist
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