Arthrogryposis in charolais cattle a study on gene penetrance.docVIP

Department of Animal Scienu The Univsrsity of Alberta (Canada) is a congenital abnormality affecting Charolais cattle and is conditioned by an autosomal recessive gene. Among pure Charolais animals in France the gene penetrance seems low while among Charolais crosses in Canada penetrance is almost complete. In a study of case histories in Canada at least five Charolais bulls that may be homozygous 3 and recessive for SAP have been identified. Such bulls show zero penetrance which is probably brought about by the selection and accumulation of modifier genes through an evolutionary Char