Assessment of the range of the HIV-1 infectivity enhancing effect of individual human semen specimen and the range of inhibition by EGCG.docVIP

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Assessment of the range of the HIV-1 infectivity enhancing effect of individual human semen specimen and the range of inhibition by EGCG.doc

Assessment of the range of the HIV-1 infectivity enhancing effect of individual human semen specimen and the range of inhibition by EGCG

Hartjenetal.AIDSResearchandTherapy2012,9:2 /content/9/1/2 RESEARCH OpenAccess AssessmentoftherangeoftheHIV-1infectivity enhancingeffectofindividualhumansemen specimenandtherangeofinhibitionbyEGCG PhilipHartjen1,3?,SebastianFrerk1,3?,IlonaHauber3,VerenaMatzat1,3,AdrianaThomssen1,3,BarbaraHolstermann3, HeinrichHohenberg3,WolfgangSchulze2,JulianSchulzezurWiesch1,3?andJanvanLunzen1,3*? Abstract Recently,ithasbeenshownthathumanejaculateenhanceshumanimmunodeficiencyvirus1(HIV-1)infectivity. Enhancementofinfectivityisconceivedtobemediatedbyamyloidfilamentsfrompeptidesthatareproteolytically released

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Assessment of the range of the HIV-1 infectivity enhancing effect of individual human semen specimen and the range of inhibition by EGCG.docVIP