原创力文档Association between polymorphisms of arachidonate 12-lipoxygenase (ALOX12) and schizophrenia in a Korean population.docVIP
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Association between polymorphisms of arachidonate 12-lipoxygenase (ALOX12) and schizophrenia in a Korean population
Kim et al. Behavioral and Brain Functions 2010, 6:44
/content/6/1/44
SHORT PAPER
Open Access
Association between polymorphisms of Short paper
arachidonate 12-lipoxygenase (ALOX12) and
schizophrenia in a Korean population
Tae Kim1,2, Hak-Jae Kim3, Jin Kyung Park4, Jong Woo Kim*1 and Joo-Ho Chung5
Abstract
Arachidonic acid (AA), an essential polyunsaturated fatty acid, is one of the major components of neural membranes,
which show an altered phospholipid composition in schizophrenia. Arachidonate 12-lipoxygenase (ALOX12), an
important enzyme, metabolizes AA to 12-HPETE, which affects cat
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