Association of MHC and rheumatoid arthritis HLA-DR4 and rheumatoid arthritis - studies in mice and men.docVIP

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Association of MHC and rheumatoid arthritis HLA-DR4 and rheumatoid arthritis - studies in mice and men.doc

Association of MHC and rheumatoid arthritis HLA-DR4 and rheumatoid arthritis - studies in mice and men

/content/2/3/208 Review Association of MHC and rheumatoid arthritis HLA-DR4 and rheumatoid arthritis: studies in mice and men Lars Fugger and Arne Svejgaard* Aarhus University Hospital, Skejby Sygehus, Denmark, and *Rigshospitalet, Copenhagen University Hospital, Denmark Received: 9 February 2000 Accepted: 29 February 2000 Published: 25 April 2000 Arthritis Res 2000,2:208–211 ? Current Science Ltd Abstract Inherited susceptibility to rheumatoid arthritis (RA) is asociated with the DRB1 genes encoding the human leukocyte antigen (HLA)-DR4 and HLA-DR1 molecules. Transgenic mice

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