Association of MHTFR Ala222Val (rs1801133) polymorphism and breast cancer susceptibility An update meta-analysis based on 51 research studies.docVIP

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Association of MHTFR Ala222Val (rs1801133) polymorphism and breast cancer susceptibility An update meta-analysis based on 51 research studies.doc

Association of MHTFR Ala222Val (rs1801133) polymorphism and breast cancer susceptibility An update meta-analysis based on 51 research studies

YuandChenDiagnosticPathology2012,7:171 /content/7/1/171 RESEARCH OpenAccess AssociationofMHTFRAla222Val(rs1801133) polymorphismandbreastcancersusceptibility: Anupdatemeta-analysisbasedon51research studies LiwaYuandJianqiuChen* Abstract Background:TheassociationbetweenMHTFRAla222Valpolymorphismandbreastcancer(BC)riskareinconclusive. Toderiveamorepreciseestimationoftherelationship,asystematicreviewandmeta-analysiswasperformed. Methods:AcomprehensivesearchwasconductedthroughresearchingMEDLINE,EMBASE,PubMed,Webof Science,ChineseBiomedicalLiteraturedatabase(CBM)andChinaNationalKnowledgeInfrastruc

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