Associations of the TNF-alpha -308?GA, IL6 -174?GC and AdipoQ 45?TG polymorphisms with inflammatory and metabolic responses to lifestyle intervention in Brazilians at high cardiometabolic risk.docVIP
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Associations of the TNF-alpha -308?GA, IL6 -174?GC and AdipoQ 45?TG polymorphisms with inflammatory and metabolic responses to lifestyle intervention in Brazilians at high cardiometabolic risk
Curtietal.DiabetologyMetabolicSyndrome2012,4:49
/content/4/1/49
DIABETOLOGY
METABOLIC SYNDROME
RESEARCH
OpenAccess
AssociationsoftheTNF-alpha-308G/A,
IL6-174G/CandAdipoQ45T/Gpolymorphisms
withinflammatoryandmetabolicresponsesto
lifestyleinterventioninBraziliansathigh
cardiometabolicrisk
MairaLRCurti,MilenaMPires,CamilaRBarros,AntonelaSiqueira-Catania,MarceloMacedoRogero
andSandraRGFerreira*
Abstract
Background:Cytokinessecretedbytheadiposetissueinfluenceinflammationandinsulinsensitivity,andleadto
metabolicdisturbances.Howcertainsingle-nucleotidepolymorphisms(SNPs)interfereonlifestyleinterv
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