Autophagy induction and CHOP under-expression promotes survival of fibroblasts from rheumatoid arthritis patients under endoplasmic reticulum stress.docVIP

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Autophagy induction and CHOP under-expression promotes survival of fibroblasts from rheumatoid arthritis patients under endoplasmic reticulum stress.doc

Autophagy induction and CHOP under-expression promotes survival of fibroblasts from rheumatoid arthritis patients under endoplasmic reticulum stress

Shinetal.ArthritisResearchTherapy2010,12:R19 /content/12/1/R19 RESEARCH ARTICLE OpenAccess AutophagyinductionandCHOPunder-expression promotessurvivaloffibroblastsfrom rheumatoidarthritispatientsunder endoplasmicreticulumstress Yong-JooShin1,Song-HeeHan2,Do-SungKim2,Geum-HwaLee2,Wan-HeeYoo3,Yong-MoKang4,Je-YongChoi5, YongChulLee6,7,SeoungJuPark6,7,Seul-KiJeong8,Hyung-TaeKim9,Soo-WanChae2,Hyun-JaJeong10, Hyung-RyongKim11,Han-JungChae2,7* Abstract Introduction:Synovialfibroblastsfromrheumatoidarthritisshowresistancetoapoptoticstimuli,indicatingthey maybedifficulttotreat.Toclearlyunderstandthes

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Autophagy induction and CHOP under-expression promotes survival of fibroblasts from rheumatoid arthritis patients under endoplasmic reticulum stress.docVIP