原创力文档Basophil sensitivity through CD63 or CD203c is a functional measure for specific immunotherapy.docVIP
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Basophil sensitivity through CD63 or CD203c is a functional measure for specific immunotherapy
Mikkelsenetal.ClinicalandMolecularAllergy2010,8:2
/content/8/1/2
CMA
RESEARCH
OpenAccess
BasophilsensitivitythroughCD63orCD203cisa
functionalmeasureforspecificimmunotherapy
SusanMikkelsen1,BoMartinBibby2,MetteKonowB?gebjergDolberg1,RonaldDahl1,HansJürgenHoffmann1,3*
Abstract
Background:SubcutaneousImmunotherapy(SCIT)modifiestheallergicresponseandrelievesallergicsymptoms.
SCITistheonlyandaveryeffectivetreatmentforinsectvenomallergy.Wehypothesizedthatbasophilsensitivity,
measuredthroughthebasophilactivationtest,woulddecreaseduringSCITupdosing.ExpressionofCD203cwas
comparedtoCD63asmarkerforbaso
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