Biomarkers for hepatocellular carcinoma progression in early diagnosis, prognosis, and personalized therapy.docVIP

Zhuetal.BiomarkerResearch2013,1:10 /content/1/1/10 REVIEW OpenAccess Biomarkersforhepatocellularcarcinoma: progressioninearlydiagnosis,prognosis,and personalizedtherapy KaiZhu1,2,ZhiDai1,2andJianZhou1,2,3* Abstract Hepatocellularcarcinoma(HCC)isoneofthemostcommonmalignanttumorsintheworld.Currently,surgical resection,livertransplantation,andlocalablationareconsideredcurativetherapeuticpracticesforHCC.The diagnosisofHCCwithoutpathologicconfirmationisachievedbyanalyzingserumalpha-fetoprotein(AFP)levels combinedwithimagingtechniques,includingultrasonography,magneticresonanceimaging,andcomputeriz