Biomarkers of focal and diffuse traumatic brain injury.docVIP

Vos Critical Care 2011,15:183 /content/15/4/183 COMMENTARY Biomarkers of focal and di?use traumatic brain injury Pieter E Vos* See related research by Mondello et al., /content/15/3/R156 normal transport to the circulation. Despite the strength Abstract of the association between existing predictors of out come, the prognostic value is still modest. Studies in more than 10,000 patients demonstrate a diagnostic accuracy of 0.70 to 0.84, which is insu? cient as a diagnostic and prog- nostic tool in individual patients [2,3]. Current models explain only 35% of the outcome