Bone marrow lesions predict site-specific cartilage defect development and volume loss a prospective study in older adults.docVIP
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Bone marrow lesions predict site-specific cartilage defect development and volume loss a prospective study in older adults
Doreetal.ArthritisResearchTherapy2010,12:R222
/content/12/6/R222
RESEARCH ARTICLE
OpenAccess
Bonemarrowlesionspredictsite-specificcartilage
defectdevelopmentandvolumeloss:a
prospectivestudyinolderadults
DawnDore1*,AshleighMartens1,StephenQuinn1,ChanghaiDing1,2,TaniaWinzenberg1,GuangjuZhai3,
Jean-PierrePelletier4,JohanneMartel-Pelletier4,Fran?oisAbram5,FlaviaCicuttini2,GraemeJones1
Abstract
Introduction:Recentevidencesuggeststhatbonemarrowlesions(BMLs)playapivotalroleinkneeosteoarthritis
(OA).Theaimsofthisstudyweretodetermine:1)whetherbaselineBMLpresenceand/orseveritypredictsite-
specificcar
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