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Brain perfusion CT compared with15O-H2O-PET in healthy subjects
Grüneretal.EJNMMIResearch2011,1:28
/content/1/1/28
ORIGINAL RESEARCH
OpenAccess
BrainperfusionCTcomparedwith15O-H2O-PETin
healthysubjects
JulieMarieGrüner*?,RunePaamand?,LiselotteH?jgaard?andIanLaw?
Abstract
Background:Regionalcerebralbloodflow[rCBF]measurementsarevaluableforidentifyingangiogenicallyactive
tumours,andperfusioncomputedtomography[CT]hasbeensuggestedforthatpurpose.Thisstudyaimedto
validaterCBFmeasurementsbyperfusionCTwithpositron-emissiontomography[PET]and15O-labelledwater[15O-
H2O]inhealthysubjects.
Methods:RCBFwasmeasuredtwicein12healthysubjectswith15O-H2OPETandoncewithperfu
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